![]() Competing interests The authors, the Journal Editor H Wood and the CME questions author D Lie declared no competing interests. 5 Describe the most appropriate treatment for TEA. 4 Identify the most likely anatomic seizure focus of patients with TEA. 3 Recognize the types of persistent amnesia seen in patients with TEA. 2 Distinguish clinical features of TEA from transient global amnesia and psychogenic amnesia. Transient epileptic amnesia (TEA) is a distinct neurologic condition occurring in late-middle/old age and presenting with amnesic attacks of epileptic nature and interictal memory disturbances. Learning objectives Upon completion of this activity, participants should be able to: 1 Describe diagnostic criteria for transient epileptic amnesia (TEA). To receive credit, please go to and complete the post-test. All other clinicians completing this activity will be issued a certificate of participation. Physicians should only claim credit commensurate with the extent of their participation in the activity. Medscape, LLC designates this educational activity for a maximum of 0.5 AMA PRA Category 1 Credits. Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide CME for physicians. KEYWORDS epilepsy, memory, MRI, PET, transient epileptic amnesia Continuing Medical Education online Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit. Investigations Physical examination, laboratory tests, EEG, MRI brain scan, PET imaging, and neuropsychological assessment. Between amnestic episodes, the patient noticed a gradual deterioration in his recall of remote events, despite normal performance on standard memory tests. The attacks were sometimes associated with olfactory hallucinations. ![]() ![]() The attacks often occurred on waking, did not affect other cognitive abilities such as perception, language or judgment, and typically lasted about half an hour. The expectation is to identify networking and connectivity changes which are unique to the condition.Abstract : Background A 54-year-old man presented to a cognitive disorders clinic having experienced recurrent episodes of transient amnesia over a number of years. Interictal memory deficits, such as autobiographic amnesia and. The main study objective is to evaluate networking and connectivity measures in patients with TEA, using resting-state EEG, and to compare these to a healthy age-matched population. TEA is a type of adult-onset temporal lobe epilepsy characterized by recurring amnestic seizures. These methods have been successfully used to gain further insight into conditions such as Alzheimer’s disease and other forms of cognitive impairment e.g. Novel methods of biomedical processing now allow the exploration of networking and connectivity within the brain, using routine EEG data. Whilst EEG is commonly used in diagnosis and management of epilepsy, in some cases the EEG is either normal or abnormalities are non-specific. Whilst episodes of amnesia in TEA are known to be associated with epilepsy, either as ictal or post-ictal manifestations, the underlying pathophysiology and network mechanisms are not well understood. The amnestic attacks may occur alongside semiology seen in temporal lobe epilepsy and the associated amnesia may be anterograde and retrograde in nature, often in conjunction with accelerated interictal long-term forgetting and atypical patchy autobiographical memory loss. Transient Epileptic Amnesia is characterised by recurrent episodes of short-lived amnesia, typically lasting less than 1hour. The aim of the study is to improve the usefulness of resting-state EEG in the diagnosis and management of patients with Transient Epileptic Amnesia (TEA). Training Location: Manchester Metropolitan University.HSST - Neurophysiology The role of cortical connectivity and functional network analysis of resting-state EEG in Transient Epileptic Amnesia (TEA)
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